31 research outputs found

    Probabilistic network coding techniques for vehicular ad-hoc networks

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    vehicular ad hoc network (vanet) is an emerging technology that enables moving vehicles on the road to connect and communicate as network devices. vanets enhance roads safety measures and improve traffic efficiency. however, due to the lack of centralization and the large number of highly mobile nodes, vanets are considered as highly congested networks with significant packet collisions and retransmissions. on the other hand, network coding is an emerging technique known to effectively utilize network resources by significantly reducing the number of transmissions. in network coding, intermediate nodes minimize the number of transmission by combining different packets before transmitting. however, a fundamental problem for network coding relay when it receives a packet is whether to wait for a coding opportunity to reduce network congestion; or to send the packet immediately without coding to reduce packet delay. this thesis proposes network coding techniques to reduce the number of transmissions and the bandwidth consumption in vanet multi-hop scenario. it also presents an analytical study on the trade-off between the average packet delay and the network throughput in network coding. it proposes a probabilistic approach for the intermediate nodes and therefore develops an analytical framework to present the effect of using such technique on the network performance. the system stability conditions have also been investigated. moreover, flows with different and same priorities are considered and different mechanisms that consider the nature of the different applications are proposed. for fair delay, this thesis provides the optimum transmission probability which achieves the minimum fair delay and results in an optimum throughput. while for different priority flows, a queue state based probabilistic scheduling schemes are proposed to avoid unbounded packet delays. to highlight the result, for symmetric rate flows, fairness scheme shows that the optimum fair delay can be achieved with probability of transmission of 0.5. it also shows that despite the flow data rate, using this probability will result in 33% improvement in the bandwidth consumption, and in an equal hop delay for both flows that is 0.5/?, where ? is the average flow data rate. moreover, for asymmetric rate flows the work provides the optimum transmission probability and its corresponding fair delay and throughput improvement. simulation is carried out to verify the analytical results where it is closely matched the theoretical results

    Survey on broadcasting in VANETs

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    This study aims to evaluate, categorize and compare the Vehicular Ad-hoc Network (VANET) broadcasting protocols. Massive amount of VANET broadcasting protocols have been proposed in the literature. Aiming efficiency, reliability, scalability and reach-ability each of them adopts certain techniques to provide a certain level of functionality. This study distinguishes the VANET routing protocols in several categorizes according to the applications it may serve. By focusing into broadcasting protocols, the study further divides the reviewed algorithms according to the techniques they used to initiate the communication, which would be either through beaconing, handshaking, or instant broadcasting. These protocols are further classified according to the criteria that have been used to select the next forwarder. The criteria usually influenced by the targeted performance of the technique. Such criteria may include furthest node from the sender, the node with the best link quality, endanger nodes, nodes with high probability of forwarding and backbone nodes. Performance metrics that are used for quantitative evaluation are suggested

    SARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study

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    Background: Preoperative SARS-CoV-2 vaccination could support safer elective surgery. Vaccine numbers are limited so this study aimed to inform their prioritization by modelling. Methods: The primary outcome was the number needed to vaccinate (NNV) to prevent one COVID-19-related death in 1 year. NNVs were based on postoperative SARS-CoV-2 rates and mortality in an international cohort study (surgical patients), and community SARS-CoV-2 incidence and case fatality data (general population). NNV estimates were stratified by age (18-49, 50-69, 70 or more years) and type of surgery. Best- and worst-case scenarios were used to describe uncertainty. Results: NNVs were more favourable in surgical patients than the general population. The most favourable NNVs were in patients aged 70 years or more needing cancer surgery (351; best case 196, worst case 816) or non-cancer surgery (733; best case 407, worst case 1664). Both exceeded the NNV in the general population (1840; best case 1196, worst case 3066). NNVs for surgical patients remained favourable at a range of SARS-CoV-2 incidence rates in sensitivity analysis modelling. Globally, prioritizing preoperative vaccination of patients needing elective surgery ahead of the general population could prevent an additional 58 687 (best case 115 007, worst case 20 177) COVID-19-related deaths in 1 year. Conclusion: As global roll out of SARS-CoV-2 vaccination proceeds, patients needing elective surgery should be prioritized ahead of the general population

    Global variation in postoperative mortality and complications after cancer surgery: a multicentre, prospective cohort study in 82 countries

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    © 2021 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY-NC-ND 4.0 licenseBackground: 80% of individuals with cancer will require a surgical procedure, yet little comparative data exist on early outcomes in low-income and middle-income countries (LMICs). We compared postoperative outcomes in breast, colorectal, and gastric cancer surgery in hospitals worldwide, focusing on the effect of disease stage and complications on postoperative mortality. Methods: This was a multicentre, international prospective cohort study of consecutive adult patients undergoing surgery for primary breast, colorectal, or gastric cancer requiring a skin incision done under general or neuraxial anaesthesia. The primary outcome was death or major complication within 30 days of surgery. Multilevel logistic regression determined relationships within three-level nested models of patients within hospitals and countries. Hospital-level infrastructure effects were explored with three-way mediation analyses. This study was registered with ClinicalTrials.gov, NCT03471494. Findings: Between April 1, 2018, and Jan 31, 2019, we enrolled 15 958 patients from 428 hospitals in 82 countries (high income 9106 patients, 31 countries; upper-middle income 2721 patients, 23 countries; or lower-middle income 4131 patients, 28 countries). Patients in LMICs presented with more advanced disease compared with patients in high-income countries. 30-day mortality was higher for gastric cancer in low-income or lower-middle-income countries (adjusted odds ratio 3·72, 95% CI 1·70–8·16) and for colorectal cancer in low-income or lower-middle-income countries (4·59, 2·39–8·80) and upper-middle-income countries (2·06, 1·11–3·83). No difference in 30-day mortality was seen in breast cancer. The proportion of patients who died after a major complication was greatest in low-income or lower-middle-income countries (6·15, 3·26–11·59) and upper-middle-income countries (3·89, 2·08–7·29). Postoperative death after complications was partly explained by patient factors (60%) and partly by hospital or country (40%). The absence of consistently available postoperative care facilities was associated with seven to 10 more deaths per 100 major complications in LMICs. Cancer stage alone explained little of the early variation in mortality or postoperative complications. Interpretation: Higher levels of mortality after cancer surgery in LMICs was not fully explained by later presentation of disease. The capacity to rescue patients from surgical complications is a tangible opportunity for meaningful intervention. Early death after cancer surgery might be reduced by policies focusing on strengthening perioperative care systems to detect and intervene in common complications. Funding: National Institute for Health Research Global Health Research Unit

    Effects of hospital facilities on patient outcomes after cancer surgery: an international, prospective, observational study

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    © 2022 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 licenseBackground: Early death after cancer surgery is higher in low-income and middle-income countries (LMICs) compared with in high-income countries, yet the impact of facility characteristics on early postoperative outcomes is unknown. The aim of this study was to examine the association between hospital infrastructure, resource availability, and processes on early outcomes after cancer surgery worldwide. Methods: A multimethods analysis was performed as part of the GlobalSurg 3 study—a multicentre, international, prospective cohort study of patients who had surgery for breast, colorectal, or gastric cancer. The primary outcomes were 30-day mortality and 30-day major complication rates. Potentially beneficial hospital facilities were identified by variable selection to select those associated with 30-day mortality. Adjusted outcomes were determined using generalised estimating equations to account for patient characteristics and country-income group, with population stratification by hospital. Findings: Between April 1, 2018, and April 23, 2019, facility-level data were collected for 9685 patients across 238 hospitals in 66 countries (91 hospitals in 20 high-income countries; 57 hospitals in 19 upper-middle-income countries; and 90 hospitals in 27 low-income to lower-middle-income countries). The availability of five hospital facilities was inversely associated with mortality: ultrasound, CT scanner, critical care unit, opioid analgesia, and oncologist. After adjustment for case-mix and country income group, hospitals with three or fewer of these facilities (62 hospitals, 1294 patients) had higher mortality compared with those with four or five (adjusted odds ratio [OR] 3·85 [95% CI 2·58–5·75]; p<0·0001), with excess mortality predominantly explained by a limited capacity to rescue following the development of major complications (63·0% vs 82·7%; OR 0·35 [0·23–0·53]; p<0·0001). Across LMICs, improvements in hospital facilities would prevent one to three deaths for every 100 patients undergoing surgery for cancer. Interpretation: Hospitals with higher levels of infrastructure and resources have better outcomes after cancer surgery, independent of country income. Without urgent strengthening of hospital infrastructure and resources, the reductions in cancer-associated mortality associated with improved access will not be realised. Funding: National Institute for Health and Care Research

    Search for pair production of first and second generation leptoquarks in proton-proton collisions at s=8\sqrt{s} = 8 TeV

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    A search for pair production of first and second generation leptoquarks is performed in final states containing either two charged leptons and two jets, or one charged lepton, one neutrino and two jets, using proton-proton collision data at s=8\sqrt{s} = 8 TeV. The data, corresponding to an integrated luminosity of 19.7 fb1^{-1}, were recorded with the CMS detector at the LHC. First-generation scalar leptoquarks with masses less than 1010 (850) GeV are excluded for β=1.0 (0.5), where β is the branching fraction of a leptoquark decaying to a charged lepton and a quark. Similarly, second-generation scalar leptoquarks with masses less than 1080 (760) GeV are excluded for β=1.0 (0.5). Mass limits are also set for vector leptoquark production scenarios with anomalous vector couplings, and for R-parity violating supersymmetric scenarios of top squark pair production resulting in similar final-state signatures. These are the most stringent limits placed on the masses of vector leptoquarks and RPV top squarks to date

    Search for Pair Production of First and Second Generation Leptoquarks in Proton-Proton Collisions at s\sqrt{s} = 8 TeV

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    A search for pair production of first and second generation leptoquarks is performed in final states containing either two charged leptons and two jets, or one charged lepton, one neutrino and two jets, using proton-proton collision data at s= \sqrt{s} = 8TeV. The data, corresponding to an integrated luminosity of 19.7 fb1^{-1}, were recorded with the CMS detector at the LHC. First-generation scalar leptoquarks with masses less than 1010 (850) GeV are excluded for β=\beta = 1.0 (0.5), where β\beta is the branching fraction of a leptoquark decaying to a charged lepton and a quark. Similarly, second-generation scalar leptoquarks with masses less than 1080 (760) GeV are excluded for β=\beta = 1.0 (0.5). Mass limits are also set for vector leptoquark production scenarios with anomalous vector couplings, and for R-parity violating supersymmetric scenarios of top squark pair production resulting in similar final-state signatures. These are the most stringent limits placed on the masses of leptoquarks and RPV top squarks to date

    Measurement of the underlying event activity using charged-particle jets in proton-proton collisions at s\sqrt{s} = 2.76 TeV

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    A measurement of the underlying event (UE) activity in proton-proton collisions is performed using events with charged-particle jets produced in the central pseudorapidity region (ηjet |{\eta^{\text{jet}}} | < 2) and with transverse momentum 1 pTjet<\le p_{\mathrm{T}}^\text{jet} \lt 100 GeV. The analysis uses a data sample collected at a centre-of-mass energy of 2.76 TeV with the CMS experiment at the LHC. The UE activity is measured as a function of pTjetp_{\mathrm{T}}^\text{jet} in terms of the average multiplicity and scalar sum of transverse momenta (pTp_{\mathrm{T}}) of charged particles, with η<2|{\eta}| \lt 2 and pT>0.5p_{\mathrm{T}} \gt 0.5 GeV, in the azimuthal region transverse to the highest pTp_{\mathrm{T}} jet direction. By further dividing the transverse region into two regions of smaller and larger activity, various components of the UE activity are separated. The measurements are compared to previous results at 0.9 and 7 TeV, and to predictions of several Monte Carlo event generators, providing constraints on the modelling of the UE dynamics

    Search for pair-produced vector-like B quarks in proton-proton collisions at s\sqrt{s} = 8 TeV

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    A search for the production of a heavy B quark, having electric charge -1/3 and vector couplings to W, Z, and H bosons, is carried out using proton-proton collision data recorded at the CERN LHC by the CMS experiment, corresponding to an integrated luminosity of 19.7 inverse femtobarns. The B quark is assumed to be pair-produced and to decay in one of three ways: to tW, bZ, or bH. The search is carried out in final states with one, two, and more than two charged leptons, as well as in fully hadronic final states. Each of the channels in the exclusive final-state topologies is designed to be sensitive to specific combinations of the B quark-antiquark pair decays. The observed event yields are found to be consistent with the standard model expectations in all the final states studied. A statistical combination of these results is performed and upper limits are set on the cross section of the strongly produced B quark-antiquark pairs as a function of the B quark mass. Lower limits on the B quark mass between 740 and 900 GeV are set at a 95% confidence level, depending on the values of the branching fractions of the B quark to tW, bZ, and bH. Overall, these limits are the most stringent to date
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